Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-04-28
2010-11-16
Anderson, Rebecca L (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C544S373000
Reexamination Certificate
active
07834020
ABSTRACT:
The invention relates to new crystalline modifications of the hydrochloride of 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine, crystalline modification of the dihydrochloride of 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine and amorphous 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoyl-benzofuran-5-yl)-piperazine hydrochloride which are suitable in particular for the preparation of solid medicaments for the treatment or prevention of depressive disorders, anxiety disorders, bipolar disorders, mania, dementia, substance-related disorders, sexual dysfunctions, eating disorders, obesity, fibromyalgia, sleeping disorders, psychiatric disorders, cerebral infarct, tension, for the therapy of side-effects in the treatment of hypogonadism, secondary amenorrhea, premenstrual syndrome and undesired puerperal lactation.
REFERENCES:
patent: 5532241 (1996-07-01), Bottcher et al.
patent: 5723614 (1998-03-01), Bathe et al.
patent: 5977112 (1999-11-01), Bathe et al.
patent: 0 648 767 (1995-04-01), None
patent: 0 738 722 (1996-10-01), None
patent: WO 00 72832 (2000-12-01), None
Summary of Facts Regarding US Clinical Trials Prior to Jun. 5, 2001.
Sorbera, L.A., et al. “Vilazodone Hydrochloride. Antidepressant 5-HT1APartial Agonist 5-HT Reuptake Inhibitor” Drugs of the Future 2001, 26(3):247-252 (Mar. 2001).
Remington Farmacia Tomo 2 19a edición, 1998.
Farmacotecnia Teorica Y Practica Tomo IV, Dr. José Helman, 1980.
Hungarian Search Report of May 10, 2010 citing HU P0201275 which corresponds to WO 00/72832.
Bartels Matthias
Bathe Andreas
Böttcher Henning
Helfert Bernd
Kniel Heike
Anderson Rebecca L
Barker Michael
Merck Patent Gesellschaft
Millen White Zelano & Branigan P.C.
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