Polymorphic forms of 3-(4-amino-1-oxo-1,3...

Details Polymorphic forms of 3-(4-amino-1-oxo-1,3... Polymorphic forms of 3-(4-amino-1-oxo-1,3...

2004-09-03

2008-12-16

Chang, Celia (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S323000

Reexamination Certificate

active

07465800

ABSTRACT:
Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione are disclosed. Compositions comprising the polymorphic forms, methods of making the polymorphic forms and methods of their use are also disclosed.

REFERENCES:
patent: 3536809 (1970-10-01), Applezweig
patent: 3598123 (1971-08-01), Zaffaroni et al.
patent: 3845770 (1974-11-01), Theeuwes et al.
patent: 3916899 (1975-11-01), Theeuwes et al.
patent: 4008719 (1977-02-01), Theeuwes et al.
patent: 4810643 (1989-03-01), Souza
patent: 4999291 (1991-03-01), Souza
patent: 5059595 (1991-10-01), Le Grazie
patent: 5073543 (1991-12-01), Marshall et al.
patent: 5120548 (1992-06-01), McClelland et al.
patent: 5229496 (1993-07-01), Deeley et al.
patent: 5354556 (1994-10-01), Sparks et al.
patent: 5385901 (1995-01-01), Kaplan et al.
patent: 5391485 (1995-02-01), Deeley et al.
patent: 5393870 (1995-02-01), Deeley et al.
patent: 5528823 (1996-06-01), Rudy, Jr. et al.
patent: 5580755 (1996-12-01), Souza
patent: 5591767 (1997-01-01), Mohr et al.
patent: 5593990 (1997-01-01), D'Amato
patent: 5629327 (1997-05-01), D'Amato
patent: 5635517 (1997-06-01), Muller et al.
patent: 5639476 (1997-06-01), Oshlack et al.
patent: 5674533 (1997-10-01), Santus et al.
patent: 5698579 (1997-12-01), Muller
patent: 5712291 (1998-01-01), D'Amato
patent: 5731325 (1998-03-01), Andrulis, Jr. et al.
patent: 5733566 (1998-03-01), Lewis
patent: 5798368 (1998-08-01), Muller et al.
patent: 5874448 (1999-02-01), Muller et al.
patent: 5877200 (1999-03-01), Muller
patent: 5929117 (1999-07-01), Muller et al.
patent: 5955476 (1999-09-01), Muller et al.
patent: 6020358 (2000-02-01), Muller et al.
patent: 6071948 (2000-06-01), D'Amato
patent: 6114355 (2000-09-01), D'Amato
patent: 6140346 (2000-10-01), Andrulis, Jr. et al.
patent: 6235756 (2001-05-01), D'Amato
patent: 6281230 (2001-08-01), Muller et al.
patent: 6316471 (2001-11-01), Muller et al.
patent: 6326388 (2001-12-01), Man et al.
patent: 6335349 (2002-01-01), Muller et al.
patent: 6380239 (2002-04-01), Muller et al.
patent: 6395754 (2002-05-01), Muller et al.
patent: 6403613 (2002-06-01), Man et al.
patent: 6420414 (2002-07-01), D'Amato
patent: 6458810 (2002-10-01), Muller et al.
patent: 6469045 (2002-10-01), D'Amato
patent: 6476052 (2002-11-01), Muller et al.
patent: 6518298 (2003-02-01), Green et al.
patent: 6555554 (2003-04-01), Muller et al.
patent: 2001/0018445 (2001-08-01), Huang et al.
patent: 2001/0056114 (2001-12-01), D'Amato
patent: 2002/0035090 (2002-03-01), Zeldis et al.
patent: 2002/0045643 (2002-04-01), Muller et al.
patent: 2002/0052398 (2002-05-01), D'Amato
patent: 2002/0054899 (2002-05-01), Zeldis
patent: 2002/0061923 (2002-05-01), D'Amato
patent: 2002/0128228 (2002-09-01), Hwu
patent: 2002/0161023 (2002-10-01), D'Amato
patent: 2002/0173658 (2002-11-01), Muller et al.
patent: 2002/0183360 (2002-12-01), Muller et al.
patent: 2003/0013739 (2003-01-01), Masferrer et al.
patent: 2003/0028028 (2003-02-01), Man et al.
patent: 2003/0045552 (2003-03-01), Robarge et al.
patent: 2003/0069428 (2003-04-01), Muller et al.
patent: 2003/0096841 (2003-05-01), Robarge et al.
patent: 2003/0139451 (2003-07-01), Shah et al.
patent: 2003/0144325 (2003-07-01), Muller et al.
patent: 2003/0181428 (2003-09-01), Green et al.
patent: 2003/0187024 (2003-10-01), D'Amato
patent: 2003/0191098 (2003-10-01), D'Amato
patent: 2003/0235909 (2003-12-01), Hariri et al.
patent: 2004/0029832 (2004-02-01), Zeldis
patent: 2004/0077685 (2004-04-01), Figg et al.
patent: 2004/0077686 (2004-04-01), Dannenberg et al.
patent: 2004/0087546 (2004-05-01), Zeldis
patent: 2004/0091455 (2004-05-01), Zeldis
patent: 2004/0122052 (2004-06-01), Muller et al.
patent: 2004/0220144 (2004-11-01), Zeldis
patent: 2004/0266809 (2004-12-01), Emanuel et al.
patent: WO 98/03502 (1998-01-01), None
patent: WO 98/54170 (1998-12-01), None
patent: WO 01/70275 (2001-09-01), None
patent: WO 01/87307 (2001-11-01), None
patent: WO 02/059106 (2002-08-01), None
patent: WO 02/064083 (2002-08-01), None
patent: PCT/US03/11578 (2003-01-01), None
Seddon “Pseudopolymorph: a polemic” Crystal Growth & design v.4(6) 1087, Web release Oct. 19, 2004.
Chen et al. “Polymorphic forms of . . . ” CA 142:303619 (2005).
Haleblian, J.; McCrone, W.;Pharmaceutical Applications of Polymorphism, Journal of Pharmaceutical Sciences, vol. 58., No. 8, Aug. 1969.
U.S. Appl. No. 60/372,348, Hariri et al.
U.S. Appl. No. 10/732,867, D'Amato et al.
U.S. Appl. No. 09/545,654, D'Amato.
U.S. Appl. No. 09/287,377, D'Amato.
Anderson, “Moving disease biology from the laboratory to the clinic,”Seminars in Oncology, 2002 29:17-20.
Barlogie et al., “High-dose therapy immunomodulatory drugs in multiple myeloma,”Seminars in Oncology, 2002, 29 (6):26-33.
Barlogie et al., “Introduction: Thalidomide and the IMiDs in multiple myeloma,”Seminars in Hematology, 2003, 40 (4):1-2.
Barlogie et al., “Total Therapy II (TTII) for newly diagnosed multiple myeloma (MM): preliminary data on feasibility and efficacy in the first 231 enrolled patients; comparison with predecessor trial total therapy I ((TTI) (N=231),”Blood, Abstract # 2857, Dec. 7-11, 2001,American Society of Hematology.
Barlogie, “Thalidomide and CC-5013 in Multiple Myeloma: The University of Arkansas experience,”Seminars in Hematology, 2003, 40 (4):33-38.
Bartlett et al., “Phase I study to determine the safety, tolerability and immunostimulatory activity of thalidomide analogue CC-5013 in patients with metastatic malignant melanoma and other advanced cancers,”British Journal of Cancer, 2004, 90:955-961.
Bartlett et al., “The evolution of thalidomide and its IMiD derivatives as anticancer agents,”Nature Reviews Cancer, 2004, 4 (4):1-9.
Battegay, “Angiogenesis: mechanistic insights, neovascular diseases, and therapeutic prospects,”J. Mol. Med., 1995, 73:333-346.
Baz et al.,“Doxil (D), vincristine (V), reduced frequency dexamethasone (d) and revlimid (R) (DVd-R) results in a high response rate in patients with refractory multiple myeloma (RMM),”Blood, Abstract # 2559,American Society of Hematology, Dec. 10-13, 2005.
Brennen et al., “Thalidomide and analogues: current proposed mechanisms and therapeutic usage,”Clinical Prostate Cancer, 2004, 3 (1):54-61.
Celgene Corporation, “Additional clinical data presented on Revimid™ in myelodysplastic sydromes at the American Society of Hematology 45thannual meeting,” Press Release, Dec. 2003.
Celgene Corporation, “Blood reports Revimid™ has anti-tumor activity in patients with relapsed and refractory multiple myeloma,” Press Release, Nov. 1, 2002.
Celgene Corporation, “Celgene advances immunomodulatory drug (IMiD™) clinical program,” Press Release, Feb. 2000.
Celgene Corporation, “Celgene announces plans to stop phase III trials in melanoma due to lack of efficacy,” Press Release, Apr. 2004.
Celgene Corporation, “Celgene corporation advances ACTIMID™ (CC-4047) into phase II trial for prostate cancer,” Press Release, Oct. 2003.
Celgene Corporation, “Celgene Corporation announces fourth quarter and full year results for 2002,” Press Release, Jan. 2003.
Celgene Corporation, “Celgene Corporation announces third quarter results. THALOMID® (thalidomide) revenue increases 41% to $30.5 million. Pivotal programs for THALOMID and REVIMID™ finalized. Peer-reviewed publications of THALOMID and REVIMID data. First JNK inhibitor advanced to Phase I clinical trial,” Press Release, Oct. 2002.
Celgene Corporation, “Celgene Corporation announces third quarter results. Thalomid® (thalidomide) sales increase 24%. Prescriptions up 50%. Enhanced S.T.E.P.S.® launched. Pilot d-MPH data presented,” Press Release, Oct. 2001.
Celgene Corporation, “Celgene Corporation receives orphan drug designation for Revimid™ for multiple myeloma,” Press Release, Oct. 2001.
Celgene Corporation, “

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