Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-09-11
2007-09-11
Kifle, Bruck (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C540S520000
Reexamination Certificate
active
11233835
ABSTRACT:
The present invention relates to novel polymorphic and amorphous forms of a phosphate salt of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one, and to processes for their preparation. Such polymorphic forms may be a component of a pharmaceutical composition and may be used to treat a mammalian disease condition mediated by poly(ADP-ribose) polymerase activity including the disease condition such as cancer.
REFERENCES:
patent: 6495541 (2002-12-01), Webber et al.
patent: 6934 (2004-06-01), None
patent: WO 00/42040 (2000-07-01), None
patent: WO 2004/087713 (2004-10-01), None
Borer Bennett Chaplin
Chu Jan-Jon
Guo Ming
Li Yi
Liu Jia
Agouron Pharmaceuticals , Inc.
Cancer Research Technology Ltd.
Kifle Bruck
Yakovleva Galina M.
Zielinski Bryan C.
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