Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-07-10
2007-07-10
McKane, Joseph K. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S313000
Reexamination Certificate
active
10276881
ABSTRACT:
The invention relates to a novel polymorph V of torasemide, to a process for its preparation, to its use as a raw material for the preparation of crystalline modifications I and III of torasemide, to amorphous torasemide modifications and to pharmaceutically acceptable salts of torasemide, to pharmaceutical forms containing the said novel polymorph V of torasemide as the active ingredient as well as to its use.
REFERENCES:
patent: 4018929 (1977-04-01), Delarge et al.
patent: 4055650 (1977-10-01), Delarge et al.
patent: RE30633 (1981-06-01), Delarge et al.
patent: 5914336 (1999-06-01), Dreckmann-Behrendt
patent: WO 00/20395 (2000-04-01), None
Masereel, B. et al, “Synthesis and pharmacology of pyrid-3-ylsufonylcyanoguanidines as diuretics,” European Journal of Medicinal Chemistry, vol. 30, No. 4, 1995, p. 343-351.
Dupont, L. et al, “Structure d'une Seconde Variete de la Torasemide,” Acta C. rystallography, Section B, Structural Crystallography and Crystal Chemistry, vol. B34, No. 8, Aug. 1978, pp. 2659-2662.
Dupont, L. et al, “Structure Cristalline et Moleculaire d'un Diuretique Derive de l'Alkyl-1[(Phenylamino-4-pyridyl-3)sulfony1]-3 Uree: la Torasemide (C15H20N4SO3),” Acta Crystallography, Section B, Structural Crystallography and Crystal Chemistry, vol. B34, No. 4, Apr. 1978, pp. 1304-1310.
Danilovski Aleksandar
Dumic Miljenko
Filic Darko
Klepić Bo{hacek over (z)}ena
Tudja Marijan
Connolly Bove & Lodge & Hutz LLP
Coppins Janet L.
McKane Joseph K.
PLIVA farmaceutska industrija dionicko drustvo
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