Polymorph of a pharmaceutical

Details Polymorph of a pharmaceutical Polymorph of a pharmaceutical

2006-09-21

2010-02-09

Stockton, Laura L. (Department: 1626)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

active

07659405

ABSTRACT:
A new crystalline polymorph of ritonavir and methods for its use and preparation are disclosed.

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Bauer, J., et al., “Ritonavir: An Extraordinary Example of Conformational Polymorphism”,Pharmaceutical Research, 18(6):859-866 (2001).
Byrn, S. R., “Solid-State Chemistry of Drugs”,Academic Press, 3-27, 79-148 (1982).
Byrn, S., et al., “Pharmaceutical Solids: A Strategic Approach to Regulatory Considerations”,Pharmaceutical Research, 12(7):945-954 (1995).
Dunitz, J. D. & Bernstein, J., “Disappearing Polymorphs”,Acc. Chem. Res., 28:193-200 (1995).
Byrn, S.R., et al., “Solid-State Pharmaceutical Chemistry”,Chem. Mater., 6, 1148-1158 (1994).
Cheronis, N. “Semimicro Experimental Organic Chemistry”, 1958, Chapter 5.

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