Polymorph of (1-benzyl-4-[(5,6-dimethoxy-1-indanone)-2-y1]...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S319000

Reexamination Certificate

active

11145202

ABSTRACT:
The present invention discloses a novel, stable polymorph of 1-benzyl-4-[(5,6-dimethoxy-1-indanone)-2-yl] methyl piperidine hydrochloride commonly known as Donepezil hydrochloride. Further the present invention discloses a process for producing Donepezil HCl amorphous and its polymorph Form (VI).

REFERENCES:
patent: 4895841 (1990-01-01), Sugimoto
patent: 5985864 (1999-11-01), Imai et al.
patent: 6734195 (2004-05-01), Weisman
patent: 1 323 712 (2003-07-01), None
patent: WO 97/46527 (1997-12-01), None
patent: WO 2004/092137 (2004-10-01), None
Usuelli, A, International Search Report (PCT/IN2004/00027), Int'l filing date Jul. 28, 2004, Apr. 13, 2005, European Patent Office, Munich, Germany.

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