Polymers with structure-defined functions

Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Aftertreated polymer

Reexamination Certificate

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Reexamination Certificate

active

07955594

ABSTRACT:
An alternating copolymer comprising a backbone of residues of a maleic anhydride derivative and those of a compound containing vinylic unsaturation, which also comprises residues of an active compound containing a nucleophilic group, bound to the backbone by a residue of the nucleophilic group, including such copolymer comprising residues of an active compound containing alcohol, thiol or amine group. The chemical and biological propertieis of actives, such as protease inhibitors, neurotransmitter drugs, and other small molecule active drugs, are enhanced, and new applications enabled. Also, artefacts, including a solid medical implant device, dressing or scaffold or a fluid adhesive or medicinal composition comprising such a polymer, and a method of use of such polymer, including a method for the treatment or prophylaxis of wounds

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http://www.acdlabs.com/iupac
omenclature/79/r79—1047.htm, accessed May 7, 2009.
Vanderbilt, D.P. and Butler, G.B., Bifunctional Synthetic Enzyme Candidates via Alternating Copolymerization, II. Copolymers Containing Alternating Imidazole and Phenolic Hydroxyl Functions, Journal of Macromolecular Science-Chemistry, vol. A23 (5), pp. 657-675 (1986).
Jeong et al., Polymeric Langmuir-Blodgett films containing imidazole-coordinated metal complexes, Polymer 41, pp. 5525-5529 (2000).

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