Polymers substituted by groups conferring anti-coagulant propert

Details Polymers substituted by groups conferring anti-coagulant propert Polymers substituted by groups conferring anti-coagulant propert

1985-09-27

1988-07-05

Rollins, John

Drug, bio-affecting and body treating compositions

Lymphokine

514 59, 514 56, 514822, 536 21, 536 51, 5253307, 525352, 525374, A61K 31745, A61K 31715, A61K 31725, C07H 506

Patent

active

047553790

ABSTRACT:
Anticoagulant products are constituted by polymers (homopolymers or copolymers) including in their chain substitutable groups on which are fixed statistically, groups X and/or Y and/or V, where X denotes the group --SO.sub.3 R.sub.1 or --R.sub.3 --SO.sub.3 R.sub.1, R.sub.1 being a hydrogen atom or a physiologically compatible metal, R.sub.3 being a --CH.sub.2 --CO--NH--R.sub.4 group in which R.sub.4 represensts an alkyl aryl or alkylaryl radical, which may or may not be substituted, or substituted or unsubstituted --CH.sub.2 --; Y denotes the group --SO.sub.2 --R.sub.2 or --R.sub.3 --SO.sub.2 --R.sub.2, R.sub.2 being the residue of an amino acid connected to the --SO.sub.2 bridge through its amine function and V denotes the group --CH.sub.2 --CO--NH--CHR--COOH, R being the side chain of an amino acid it being understood that: (a) if X is --SO.sub.3 R.sub.1 it is necessarily accompanied by Y and/or by V, and (b) V is always accompanied by X and/by Y.

REFERENCES:
patent: 3211617 (1965-10-01), Bucourt
patent: 3475358 (1969-10-01), Bixler et al.
patent: 3697498 (1972-10-01), Browning et al.
patent: 3766104 (1973-10-01), Bonin et al.
patent: 3862309 (1975-01-01), Krochock
patent: 3893890 (1975-07-01), Wurzburg
patent: 3907755 (1975-09-01), Margraff
patent: 3961045 (1976-06-01), Wurzburg et al.
patent: 3987163 (1976-10-01), Rankin
patent: 3998796 (1976-12-01), Sleinhardt
patent: 4095000 (1978-06-01), Brenner
patent: 4116898 (1978-09-01), Dudley et al.
patent: 4119616 (1978-10-01), O'Farrell et al.
patent: 4271151 (1981-06-01), Hoffa et al.
patent: 4303786 (1981-02-01), Goldstein et al.
Vesa, Moroscikas, CA. 77 115177V (1972), Dissymmetric Ion-Exchange Resins Derived from amino Acids and Chlorosulfonated Styren-Divinyl Benzene Copolymers.
Chem. Abst., 77: 115,177u, 1972.

Affiliated with

Also associated with

Rating

Polymers substituted by groups conferring anti-coagulant propert does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polymers substituted by groups conferring anti-coagulant propert, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polymers substituted by groups conferring anti-coagulant propert will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2331490