Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1994-12-23
1997-11-04
Campbell, Eggerton A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 912, C12Q 168, C12P 1934
Patent
active
056838727
ABSTRACT:
A method of detecting nucleic acid sequences in which polymers of selected oligonucleotide probes which are complementary to a region in a nucleic acid sequence that is to be detected are bound to a substrate. The polymers bound to the substrate contain multiple randomly repeated copies of a specific oligonucleotide probe and may be synthesized using enzymatic amplification techniques.
REFERENCES:
patent: 5124246 (1992-06-01), Urden et al.
patent: 5212059 (1993-05-01), Schwartz et al.
Saiki et al PNAS 86: 6230-6234 (1989).
Mullis, Cold Spring Harbor Symp. 263-273 (1986) "Specific enzymatic amplification . . . " USB Catalogue (1990) p. 152.
Roewer et al. Electrophoresis: 12(2-3):181-186 (1991) "Hybridization and PCR . . . ".
Saiki et al. PNAS 86:6230-6234 (1989) "Genetic analysis of amplified DNA . . . ".
Murray et al., Mol. Biochem. Porasit. 30:209-216 (1988) "Cloning and characterization of a species . . . ".
Matthews et al., Analyt. Biochem 169:1-25 (1988) "Analytical strategies for the use of DNA probes".
Rudert William A.
Trucco Massimo
Campbell Eggerton A.
University of Pittsburgh
LandOfFree
Polymers of oligonucleotide probes as the bound ligands for use does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Polymers of oligonucleotide probes as the bound ligands for use , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polymers of oligonucleotide probes as the bound ligands for use will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1832189