Polymers for the purification of acarbose

Details Polymers for the purification of acarbose Polymers for the purification of acarbose

1985-10-10

1987-05-19

Schofer, Joseph L.

Stock material or miscellaneous articles

Coated or structually defined flake, particle, cell, strand,...

Particulate matter

521 37, 526304, B01J 3920, B32B 516

Patent

active

046667768

ABSTRACT:
In the purification of acarbose by contacting an acarbose-containing solution with a cation exchanger to adsorb the acarbose, eluting the ion exchanger and collecting an eluate fraction enriched in purified acarbose, the improvement wherein the cation exchanger is a polymer obtained by polymerizing an aromatic compound possessing at least one vinyl group and at least one hydrophilic monomer in the presence of a solvent for the monomer which is a precipitant for the crosslinked polymer formed, isolating the resistant polymer, and sulphonating the polymer in the presence of a swelling agent for the polymer. The invention gives shapr separation and other processing advantages.

REFERENCES:
patent: 3860563 (1975-01-01), Kotsimbos
patent: 4246156 (1981-01-01), Heins et al.
patent: 4382124 (1983-05-01), Meitzna et al.
Chemistry of Synthetic High Polymers, Robert W. Lenz, pp. 359-369.

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