Polymers for the delivery of bioactive agents and methods of...

Details Polymers for the delivery of bioactive agents and methods of... Polymers for the delivery of bioactive agents and methods of...

2007-12-18

2007-12-18

Woodward, Ana (Department: 1711)

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Polymer of an ethylenically unsaturated reactant with a...

C528S288000, C528S332000, C528S335000, C528S363000, C526S310000, C526S312000, C526S318000, C526S328000, C424S078370

Reexamination Certificate

active

10601262

ABSTRACT:
Provided is a poly(amino ester) having a polymer backbone comprising at least one secondary amine linkage and at least one tertiary amine linkage in the polymer backbone. Poly(amino ester)s are prepared via the Michael addition of a bis(acrylate ester)monomer to a diamine monomer, wherein the diamine monomer has one primary amino group and one secondary amino group, and can be end-capped by reaction with a suitable reagent. The inventive poly(amino ester)s may be used as vectors for delivery of a bioactive agent, such as DNA, to a cell.

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