Polymerization-induced separation immunoassays

Details Polymerization-induced separation immunoassays Polymerization-induced separation immunoassays

1984-11-07

1987-12-08

Kepplinger, Esther M.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 6, 436501, 436504, 436513, 436531, 436533, 436534, 436538, 436539, 436548, 436800, 525904, 5262381, 527202, G01N 33537, C12Q 168

Patent

active

047118407

ABSTRACT:
Immunoassay methods and compositions are disclosed for the detection of one or more analytes in fluid samples. The disclosure provides conjugates of analytes or reactants with polymerizable organic monomers. Specific binding reactions between reactants are detected by means of reporter/reactant conjugates. Free and specifically-bound reporter/reactant conjugates are separated by a polymerization reaction which renders the polymerized monomers insoluble.

REFERENCES:
patent: 2853457 (1958-09-01), Gates et al.
patent: 3969287 (1976-07-01), Jaworek et al.
patent: 4061466 (1977-12-01), Sjoholm et al.
patent: 4469796 (1984-09-01), Axen et al.
patent: 4609707 (1986-09-01), Nowinski

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