Polymeric orthoesters housing beneficial drug for controlled rel

Details Polymeric orthoesters housing beneficial drug for controlled rel Polymeric orthoesters housing beneficial drug for controlled rel

1976-04-08

1978-01-03

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

260 2R, 424230, 424238, 424265, 424267, 424273R, 424310, 424324, 424330, A61K 3174

Patent

active

040667472

ABSTRACT:
This invention concerns polymeric orthoesters having a repeating mer comprising a hydrocarbon radical and an orthoester functionality of the general formula: ##STR1## wherein R.sub.1 is a monovalent radical, R.sub.2 is a hydrocarbon radical, a is 2 to 3, and n is at least 10. The polymers are useful for making articles of manufacture and as coatings for beneficial agents.

REFERENCES:
patent: 3887699 (1975-06-01), Yolles
patent: 3911098 (1975-10-01), Capozza
patent: 3914402 (1975-10-01), Shell

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