Polymeric diffusion matrix containing propranolol

Details Polymeric diffusion matrix containing propranolol Polymeric diffusion matrix containing propranolol

1983-03-30

1984-07-17

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424 14, 424 16, 424 19, 424 22, 424 78, 424 80, A61L 1503, A61F 1300, A61K 970, A61K 4700

Patent

active

044605625

ABSTRACT:
A self-supporting polymeric diffusion matrix provides for the sustained release of propranolol in order to deliver the propranolol to a patient. The matrix comprises from about 1 to about 60% of a polar plasticizer, from about 6 to about 30% by weight polyvinylalcohol, from about 2 to about 30% by weight polyvinylpyrrolidone, and a pharmaceutically effective amount of propranolol to provide a sustained release of propranolol over a prolonged period.

REFERENCES:
patent: 2127896 (1938-10-01), Vohrer
patent: 2138751 (1938-11-01), Vohrer
patent: 2155658 (1939-04-01), Herrmann et al.
patent: 2160503 (1939-05-01), Herrmann
patent: 2340866 (1944-02-01), Dangelmajer
patent: 2491642 (1949-12-01), Brant
patent: 2693438 (1954-11-01), Ward
patent: 3249109 (1968-05-01), Maeth
patent: 3287222 (1966-11-01), Larde et al.
patent: 3598123 (1971-08-01), Zaffaroni
patent: 3742951 (1973-07-01), Zaffaroni
patent: 3972995 (1976-08-01), Tsuk et al.
patent: 4076798 (1978-02-01), Casey et al.
patent: 4210633 (1980-07-01), Takruri et al.
patent: 4394390 (1983-07-01), Hussain et al.
Agosti, C.A. 70 #27435r (1969).
Bartsch et al., C.A. 73 #107928T (1970).
Wagner et al., C.A. 80 #22523B (1974).
Kates, C.A. 88 #163815A (1978).
Hussain et al. (II), C.A. 91 #186397s (1979).
Henry et al., C.A. 92 #15196s (1980).
Hussain et al. (III), C.A. 94 #90211N (1981).
De Boer et al. (I), C.A. 94 #131922r (1981).
De Boer et al. II, C.A. 94 #185504z (1981).
Peierls Modern Plastics 18: 53-56, Feb. 1941, Polyvinyl Alcohol Plastics.
Hess et al., Rubber Age 53: 431-433, Aug. 1943, Molding Polyvinyl Alcohol.
Ita et al., Bulletin Pharm. Research Inst. Osaka Medical College (2) 1-3 (1951) II, "On a New Water-Soluble Ointment."
Hirai Bull. Inst. Chem. Koyoto Univ., 33: 21-37 (1955), The Gel-Elasticity of High Polymers.
Langhammer et al., Naturwissen Schaften, 43: 125-126 (1956) (PVP-PVA), (PVP-PVA), Nehring Plaste und Kautschuk, 3: 279-280 (1956).
Ward et al., Amer. Perf. & Cosmetics, 79: 53-55, Nov. 1964, The use of Polyvinyl Alcohol in Film-Forming Bases.
Ward et al., J. Soc. Cos. Chem., 15: 327-335 (1964), Cosmetic Applications of Polyvinyl Alcohol.
Toyoshima, K., "Compatibility of Polyvinyl Alcohol with other Water-Soluble High Polymers," in Finch et al., Ed. (1967), Polylvinyl Alcohol: Properties & Applications, 535-553.
Ban et al., Pharmazie 29H9: 597-602 (1974) (PVP-PVA).
Nagy et al., "Formation of Disperse Structures in Polymer Gels," Proc. Int. Conf. Colloid & Surface Science, Budapest, Hungary, Sep. 1975, Wolfram Ed., pp. 447-453.

Affiliated with

Also associated with

Rating

Polymeric diffusion matrix containing propranolol does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polymeric diffusion matrix containing propranolol, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polymeric diffusion matrix containing propranolol will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1490468