Polymeric diffusion matrix containing ester derivatives of estra

Details Polymeric diffusion matrix containing ester derivatives of estra Polymeric diffusion matrix containing ester derivatives of estra

1980-12-17

1982-03-23

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

128268, 128260, 424 78, 424 80, A61F 1300, A61K 970, A61L 1503, A61K 3179

Patent

active

043212522

ABSTRACT:
There is disclosed a polymeric diffusion matrix for the sustained release of an estradiol ester by delivery to a patient requiring uterine wall maintenance or other types of estrogen therapy wherein the matrix comprises a polar plasticizer, polyvinylalcohol, polyvinylpyrrolidone, and a pharmaceutically effective amount of estradiol ester.

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Victor, et al., Contraception 1977 16(2): 125-135 Collagen Bands: A New Vaginal Delivery System for Contraceptive Steroids.
WO 80/00916 (15.05.80), Teijen Limited Sustained-Release Preparations Used in Adhesive Contact with Wet Surface, 23 pp.

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