Polymeric diffusion matrix

Details Polymeric diffusion matrix Polymeric diffusion matrix

1982-09-30

1984-08-21

Rose, Shep R.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424 22, 424 78, A61K 970, A61L 1503

Patent

active

044669534

ABSTRACT:
A polymeric diffusion matrix is provided comprising from about 2 to about 60% glycerol, from about 2 to about 15% polyvinylalcohol, from about 2 to about 10% water soluble polymer with hydration sites which in combination with the remaining ingredients yields a matrix capable of sustained release of a drug dispersed therein, and the balance water, the percentages being by weight.

REFERENCES:
patent: 2127896 (1939-10-01), Vohrer
patent: 2138751 (1938-11-01), Vohrer
patent: 2155658 (1939-04-01), Herrmann et al.
patent: 2160503 (1939-05-01), Herrmann
patent: 2340866 (1944-02-01), Dangelmajer
patent: 2491642 (1949-12-01), Brant
patent: 2693438 (1954-11-01), Ward
patent: 3287222 (1966-11-01), Larde et al.
patent: 4210633 (1980-07-01), Takrurl et al.
Riegelman, Clin. Pharm. & Therapeutics, 16, (Part 2): 873-883, (1974), "Pharmacokinetics Factors Affecting Epidermal Penetration and Percutaneous Absorption".
Brooker et al., C.A. 84: 1557070, (1976), Topical Veterinary Sedative Ger. Off., 2537203, Fisions, C.A. 90:612Y9T, (1979), (Belg. 865088).
Van Dam, C.A. 55: 9674i-9675a, (1961), Current Concepts in Therapy New Engl., J. Med., 263:748-750, 963-965, (1960).
Goldblum et al., C.A. 49:507a, (1955), Barbiturate Concentrations in Skin.
Loth, C.A. 93:155742n, (1980), Gordean Knots of Biopharmaceutics.
Dtsh. Apoth-2tg., (19800, 120(19):846-852, (Ger.), (Phenobarbitol-Skin Drug Delivery).
Peierls Modern Plastics, 18:53-56, Feb. 1941, Polyvinyl Alcohol Plastics.
Hess et al., Rubber Age, 53:431-433, Aug. 1943, Molding Polyvinyl Alcohol.
Ita et al., Bulletin Pharm. Research Inst., Osaka Medical College, (2) 1-3, (1951), II, "On a New Water-Soluble Ointment".
Hirai Bull. Inst. Chem. Koyoto Univ., 33: 21-37, (1955), The Gel-Elasticity of High Polymers.
Langhammer et al., Naturwissen Schaften, 43: 125-126, (1956), (PVP-PVA).
(PVP--PVA) Nehring Plaste und Kautschuk, 3: 277-280, (1956).
Ward et al., Amer. Perf. & Cosmetics, 79:53-55, Nov. 1964, The Use of Polyvinyl Alcohol in Film-Forming Bases.
Ward et al., J. Soc. Cos. Chem., 15:327-335, (1964), Cosmetic Applications of Polyvinyl Alcohol.
Toyoshima, K., "Compatibility of Polyvinyl Alcohol with Other Water-Solublle High Polymers" in Finch et al., ED (1967), Polyvinyl Alcohol: Properties & Applications, 535-553.
Ban et al., Pharmazie, 29 H9:597-602, (1974), (PVP-PVA).
Nagy et al., "Formation of Disperse Structures in Polymer Gels", Proc. Int. Conf. Colloid & Surface Science, Budapest, Hungary, Sep. 1975, Wolfram ed., pp. 447-453.

Affiliated with

Also associated with

Rating

Polymeric diffusion matrix does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polymeric diffusion matrix, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polymeric diffusion matrix will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1937166