Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1993-06-02
1997-12-30
Bawa, Ph.D., Raj
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424423, 424424, 424426, 424427, 424430, 424434, 424437, 523105, 523113, A61K 920
Patent
active
057027161
ABSTRACT:
The invention is directed to an improved system for controlled release of biologically active materials and to a liquid composition for its formation. The liquid composition is composed of a thermoplastic polymer, rate modifying agent, bioactive material and organic solvent. The liquid composition is capable of forming a biodegradable and/or bioerodible microporous, solid polymer matrix. The matrix is useful as an implant in patients (humans and animals) for delivery of biologically active substances to tissues or organs.
REFERENCES:
patent: 2155658 (1939-04-01), Herrmann
patent: 3068188 (1962-12-01), Beste
patent: 3219527 (1965-11-01), Gurney
patent: 3328246 (1967-06-01), Gottfried
patent: 3458622 (1969-07-01), Hill
patent: 3767784 (1973-10-01), Glick
patent: 3887699 (1975-06-01), Yolles
patent: 3931678 (1976-01-01), O'Sullivan
patent: 4088798 (1978-05-01), Michaelis
patent: 4127127 (1978-11-01), Wong
patent: 4161948 (1979-07-01), Bichon
patent: 4447562 (1984-05-01), Ivani
patent: 4450150 (1984-05-01), Sidman
patent: 4491479 (1985-01-01), Lauchenauer
patent: 4568536 (1986-02-01), Kronenthal
patent: 4570629 (1986-02-01), Widra
patent: 4582640 (1986-04-01), Smestad
patent: 4614787 (1986-09-01), Szycher
patent: 4631188 (1986-12-01), Stoy
patent: 4650665 (1987-03-01), Kronenthal
patent: 4677139 (1987-06-01), Feinmann
patent: 4715369 (1987-12-01), Suzuki
patent: 4745160 (1988-05-01), Churchill
patent: 4767627 (1988-08-01), Caldwell
patent: 4772470 (1988-09-01), Inoue
patent: 4774227 (1988-09-01), Piez
patent: 4920203 (1990-04-01), Tang
patent: 4933182 (1990-06-01), Higashi
patent: 4938763 (1990-07-01), Dunn
patent: 4946870 (1990-08-01), Partain III
patent: 5077049 (1991-12-01), Dunn
Juni et al., Chem. Pharm. Bull. 33:1609 (1985).
Dunn Richard L.
Tipton Arthur J.
Atrix Laboratories, Inc.
Bawa, Ph.D. Raj
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