Polymeric carriers for non-covalent drug conjugation

Details Polymeric carriers for non-covalent drug conjugation Polymeric carriers for non-covalent drug conjugation

1988-09-23

1993-10-12

Russel, Jeffrey E.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Blood proteins or globulins, e.g., proteoglycans, platelet...

424 8591, 435188, 530350, 530351, 530362, 530363, 5303919, 530392, 530399, 530402, A61K 3702, A61K 3944, C07K 308

Patent

active

052527131

ABSTRACT:
Polymeric carriers are polypeptides comprising at least one drug-binding domain that non-covalently binds a drug. A polymeric carrier may be attached to an antibody specific for desired target cells to form immunoconjugates that deliver a drug to the target cells in vivo. The carriers are derived from drug-binding proteins and produced through peptide synthesis or recombinant DNA technology.

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