Polymeric carrier for a controlled synthesis of peptides

Details Polymeric carrier for a controlled synthesis of peptides Polymeric carrier for a controlled synthesis of peptides

1975-02-13

1978-03-14

Lieberman, Allan

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

260 25B, 526 16, C08J 900, C08J 922

Patent

active

040790215

ABSTRACT:
An acrylic polymer suitable for use as carrier in the controlled synthesis of polypeptides is provided. The polymer comprises the condensation product of a monomer selected from the group consisting of hydroxyalkyl acrylates and hydroxyalkyl methacrylates, a polyfunctional cross-linking monomer selected from the group consisting of alkylene diacrylates, alkylene dimethacrylates, polyacrylates and polymethacrylates of polyalochols, alkylene bisacrylamides and divinylbenzene, and an aromatic ring-containing compound selected from the group consisting of aromatic acids and their anhydrides and chlorides, aromatic isocyanates, halogenophenylsilanes, and aromatic epoxy compounds. The condensate has its aromatic rings chlormethylated. The first monomer and the polyfunctional cross-linking monomer are copolymerized and the resultant copolymer is condensed with said compounds which contain an aromatic ring.

REFERENCES:
patent: 3575946 (1971-04-01), Chromocek et al.
patent: 3663467 (1972-05-01), Albright
patent: 3699089 (1972-10-01), Wichterle

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