Polymeric broad-spectrum antimicrobial materials

Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic... – Skin burn or open wound treatment

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Details

424445, 424431, 424411, 424423, 424667, 424 7826, 523122, 521 82, 525 61, A61K 31765, A61K 3118, A61L 1503, A61F 1300

Patent

active

050716484

ABSTRACT:
A sustained and controlled release form of iodine is achieved by a complex of polyvinyl alcohol and the iodine characterized by a low water solubility. The polyvinyl alcohol may be reacted to form hydroxylated polyvinyl acetal sponge and the sponge is topically applied as an antimicrobial agent which releases controlled amounts of iodine sufficient to kill germ cells with minimal toxicity to surrounding tissue.

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CA 104:225596q, Oishi et al., "Effects of the Degree of Hydration of Swollen Poly(vinyl Alcohol) Films on their Iodine Complexes", (1986).
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CA 68:50501p, Savko et al., "Absorption Spectra of Poly(vinyl Alcohol) Films Colored in Solutions in Iodides and Bromides" (1967).
CA 109:120443n, Gribov et al., "Nature of the Conducting Properties of Polymeric-Film Detectors Based on Polyvinyl . . . " (1988).

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