Polymeric blends with zwitterionic groups

Details Polymeric blends with zwitterionic groups Polymeric blends with zwitterionic groups

1998-01-26

2000-11-21

Merriam, Andrew E. C.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Processes of preparing a desired or intentional composition...

523331, 523340, 523106, 524515, 524519, 524521, 524523, 524547, 525209, 525183, 525217, 424499, C08L10102, C08L10100

Patent

active

061504327

ABSTRACT:
Disclosed is a polymer blend composition and shaped article, and a process of blending and making shaped articles of polymer blends in which the biocompatibility of various polymers is improved by blending with them a polymer including a zwitterionic group. The zwitterionic group is usually an ammonium phosphate ester, preferably a choline, zwitterionic group and the polymer containing it may be produced by the free radical polymerization of ethylenically unsaturated monomers including a monomer bearing the zwitterionic group. Blending of the two polymers may be achieved by dry blending particulate polymers or by mixing the polymers in liquid dispersion or solution followed by removal of the liquid medium. The fibrinogen absorption and/or platelet activation of polymers may be reduced to a value of less than 80% or even less than 60% of the base polymer by introducing amounts of more than 10% or more than 30% of the zwitterionic group containing polymer.

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