Polymeric anti-tumor agent and method of preparation

Details Polymeric anti-tumor agent and method of preparation Polymeric anti-tumor agent and method of preparation

1980-12-29

1983-08-09

Schofer, Joseph L.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

524378, 5253274, C08F22240, C08F 830, A61K 3174

Patent

active

043979955

ABSTRACT:
An improved pharmaceutically active derivative of a copolymer of olefin monomer and .alpha.,.beta.-unsaturated polycarboxylic anhydride is prepared by reacting the copolymer with aqueous ammonia, spray drying the resulting aqueous solution of half-amide, half-ammonium salt and thermally imidating the resulting substantially dry, solid particulate product by simultaneous treatment with elevated temperature and removal of water until 5-40% of the derivative half-amide, half-ammonium salt groups are converted to imide groups.

REFERENCES:
patent: 2854357 (1958-01-01), Johnson et al.
patent: 2883287 (1959-04-01), Fields et al.
patent: 2892736 (1959-06-01), Johnson et al.
patent: 2930775 (1960-03-01), Fordyce et al.
patent: 2957767 (1960-10-01), Williams
patent: 3157595 (1964-11-01), Johnson et al.
patent: 3261798 (1966-07-01), Farley
patent: 3282879 (1966-11-01), Werner, Jr.
patent: 3651171 (1972-03-01), von Bonin et al.
patent: 3840499 (1974-10-01), Di Giulio
patent: 4255537 (1981-03-01), Fields et al.
U.S. Patent application Ser. No. 5,638 to Joseph E. Fields et al., filed Jan. 22, 1979.

Affiliated with

Also associated with

Rating

Polymeric anti-tumor agent and method of preparation does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polymeric anti-tumor agent and method of preparation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polymeric anti-tumor agent and method of preparation will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-587830