Polymeric agent for releasing 5-aminosalicylic acid or its salts

Details Polymeric agent for releasing 5-aminosalicylic acid or its salts Polymeric agent for releasing 5-aminosalicylic acid or its salts

1978-12-20

1980-02-26

Levin, Stanford M.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

260DIG47, 424 78, 424 81, 424 83, 528172, 528424, 525 56, 525326, 525327, 525329, 525330, 525334, 525336, 525434, 525437, 525403, 525523, C08F 832, A61K 31785, C08G 6376, C08G 8500

Patent

active

041907167

ABSTRACT:
A generic polymeric agent for releasing 5-aminosalicylic acid or its salts is disclosed which comprises a nonabsorbable pharmacologically acceptable organic polymer backbone containing aromatic rings to which are covalently bonded via azo bonds a plurality of salicylic acid or salicylate salt groups. The azo bonds attach to the salicylates' 5-position carbon. The polymers undergo bacterial cleavage in the mammalian lower bowel to release 5-aminosalicylic acid and/or its salts.

REFERENCES:
patent: 3484390 (1969-12-01), Bauman et al.

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