Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage
Patent
1995-06-06
1999-10-19
Marschel, Ardin H.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving virus or bacteriophage
435 6, 436501, 436 63, 514 44, 536 231, 536 241, 536 243, 536 2431, 536 2432, 536 2433, 935 77, 935 78, C12Q 168
Patent
active
059687304
ABSTRACT:
The present invention relates to methods of monitoring, via polymerase chain reaction, the clinical progression of human immunodeficiency virus infection and its response to antiretroviral therapy. According to the invention, polymerase chain reaction assays may be used to predict immunological decline and to identify, at an early stage, patients whose infection has become resistant to a particular antiretroviral drug regimen.
REFERENCES:
patent: 5110802 (1992-05-01), Cantin et al.
Holiday et al. (1991) J. Clin. Invest., vol. 88, pp. 1755-1759.
Murakawa et al. (1988) DNA, vol. 7, No. 4, pp. 287-295.
Hart et al. (1988) The Lancet, vol. of Sep. 10, 1988, pp. 596-599.
Fitzgibbon et al. (1991) Aids Research and Human Retroviruses, vol. 7, No. 3, pp. 265-269.
Otlmann et al. (1991) Journal of Virological Methods, vol. 31, pp. 273-284.
Holodniy et al. (1991) Abstract 704 presented at the 31st Interscience Conference on Antimicrobial Agents and Chemotherapy, McCormick Place, Chicago, Illinois Sep. 29-Oct. 2, 1991, p. 216.
Holodniy et al; "Quantitation of HIV-1 RNA in the Serum of ARC and Aids Patients Using the Polymerase Chain Reaction (PCR)", Abstract presented at the Sixth International Conference on AIDS, San Francisco, California, Jun. 22, 1990.
Holodniy et al., "Quantitation of HIV-RNA in Serum and Correlation with Disease Status Using the Polymerase Chain Reaction (PCR)", Journal of Cellular Biochemistry, Supplement 14D, 1990, Abstract of UCLA Symposia on Molecular and Cellular Biology, Mar. 11-Apr. 6, 1990.
Winters, et al., "Rapid Detection of HIV Infectivity and Measurement of Antiviral Activity Using the Polymerase Chain Reaction (PCR)", Journal of Cellular Biochemistry, Supplement 15E, 1991, Abstract of Keystone Symposia on Molecular and Cellular Biology, Mar. 8-Mar. 26, 1991.
Holodniy Mark
Katzenstein David A.
Merigan Thomas C.
Leland Stanford Junior University
Marschel Ardin H.
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