Polymerase chain reaction assays for monitoring antiviral therap

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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435 6, 435 911, 435 912, 435 9151, 536 231, 536 243, 536 2431, 536 2452, 536 2433, 436 63, 436501, 436601, C12Q 170, C12Q 168, C12P 1934, C07H 2104

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058560866

ABSTRACT:
The present invention relates to methods of monitoring, via polymerase chain reaction, the clinical progression of human immunodeficiency virus infection and its response to antiretroviral therapy. According to the invention, polymerase chain reaction assays may be used to predict immunological decline and to identify, at an early stage, patients whose infection has become resistant to a particular antiretroviral drug regimen.

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