Polymerase chain reaction assays for monitoring antiviral...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

Reexamination Certificate

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C435S006120, C435S091200, C435S183000, C435S287200, C536S023100, C536S023720, C536S024330

Reexamination Certificate

active

07129041

ABSTRACT:
The present invention relates to methods of monitoring, via polymerase chain reaction, the clinical progression of human immunodeficiency virus infection and its response to antiretroviral therapy. According to the invention, polymerase chain reaction assays may be used to predict immunological decline and to identify, at an early stage, patients whose infection has become resistant to a particular antiretroviral drug regimen.

REFERENCES:
patent: 5968730 (1999-10-01), Merigan et al.
patent: 6503705 (2003-01-01), Kozal et al.
Complaint, dated Oct. 14, 2005, as filed inThe Board of Trustees of The Leland Stanford Junior University v. Roche Molecular Systems , Inc., Case No. C 05 04158 JCS, pending in United States District Court for the Northern District of California.
Defendants' Answer and Counterclaims, dated Nov. 17, 2005, as filed in theThe Board of Trustees of The Leland Stanford Junior University v. Roche Molecular Systems, Inc., Case No. C 05 04158 MHP, pending in the United States District Court for the Northern District of California.
Plaintiff and Counterdefendant Stanford's Reply to Counterclaims and Counterdefendant Thomas Merigan's Answer to Counterclaims, dated Dec. 21, 2005, as filed inThe Board of Trustees of The Leland Stanford Junior University v. Roche Molecular Systems, Inc., Case No. C 05 04158 MHP, pending in United States District Court for the Northern District of California.

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