Polymer-modified synthetic proteins

Details Polymer-modified synthetic proteins Polymer-modified synthetic proteins

2006-10-10

2006-10-10

Russel, Jeffrey Edwin (Department: 1654)

Drug, bio-affecting and body treating compositions

Lymphokine

C530S350000, C530S351000, C530S395000, C530S402000, C530S409000, C530S410000, C424S085200, C424S085400, C514S002600, C514S008100, C514S021800

Reexamination Certificate

active

07118737

ABSTRACT:
The present invention relates to methods and compositions for modifying peptides, polypeptides and proteins with polymers, especially glyco-mimetic polymers, so as to improve their biological activity or pharmacokinetic properties. The invention further provides methods and uses for such polymer-modified peptides, polypeptides and proteins. The invention is particularly suitable for use in the synthesis of polymer-modified synthetic bioactive proteins (FIG.1D), and of pharmaceutical compositions that contain such proteins.

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