Polymer modified porous substrate for solid phase extraction

Details Polymer modified porous substrate for solid phase extraction Polymer modified porous substrate for solid phase extraction

2011-04-19

2011-04-19

Therkorn, Ernest G (Department: 1776)

Liquid purification or separation

With means to add treating material

Chromatography

C210S635000, C210S656000, C210S502100

Reexamination Certificate

active

07927486

ABSTRACT:
A polymer modified porous substrate for solid phase extraction or chromatography, comprising a porous substrate and a polymeric monolith formed thereon, wherein the polymeric monolith comprises C5-10monocyclic or bicyclic aryl or heteroaryl, optionally substituted with -L-Qp-Rq; where q is 0-3, p is 0-5, Q is —NRC(O)—, —C(O)NR—, —OC(O)NR—, —OC(O)R—, —NRC(O)O—, —NRC(O)NR—, —NCO, —CHOHCHOH—, CH2OCHCH2O—, —(CH2CH2O)s—, —(CH2CH2CH2O)s—, —C(O)—, —C(O)O—, —CH2C(O)CH2—, —S—, —SS—, —CHOH—, —O—, —SO—, —SO2—, —SO3—, —OSO3, —SO2NR—, —NRq—, and —NRq+—, —CN, —NC, —CHOCH—, —NHC(NH)NH—, —NO2, —NO, —OPO3—, —OH; and R is hydrogen, C5-10monocyclic or bicyclic aryl or heteroaryl, C1-12branched, unbranched, or cyclic hydrocarbyl; L is a bond or a C1-12branched, unbranched, or cyclic hydrocarbyl. Methods of preparing and using the polymer modified porous substrates are disclosed.

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