Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving oxidoreductase
Reexamination Certificate
2005-02-22
2005-02-22
Naff, David M. (Department: 1651)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving oxidoreductase
C435S014000, C435S025000, C435S175000, C435S176000, C435S180000, C435S182000, C435S287100, C435S817000
Reexamination Certificate
active
06858403
ABSTRACT:
Hydrogels containing catalase co-immobilized with an analyte-sensitive enzyme such as glucose oxidase are disclosed. The hydrogels may be pH-sensitive, and preferably are thin and lightly crosslinked. The catalase is present in concentrations ranging generally from 100 units/ml to about 1000 units/ml. These hydrogels have much faster swelling response times as compared to hydrogels without catalase, and are useful in biosensors and analyte-responsive drug delivery devices. The hydrogels also have an increased useful life, due to protection of the immobilize analyte-sensitive enzyme from degradation by hydrogen peroxide.
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Han In Suk
Jung Dal-Young
M-Biotech, Inc.
Mallinckrodt Robert R.
Mallinckrodt & Mallinckrodt
Naff David M.
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