Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Reexamination Certificate
2008-05-13
2008-05-13
Nashed, Nashaat T. (Department: 1656)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
Reexamination Certificate
active
07371399
ABSTRACT:
Formulations and methods for treating joints, such as temporomandibular joint disorders, osteoarthritis of the knee, hip and other types of inflammatory joint diseases. The method involves identifying specific matrix metalloproteinases (MMPs) that may be responsible for degrading the soft tissues of the joint in question, identifying the specific component of the joint the MMP(s) are targeting, and injecting a polymer gel with the component the MMP(s) seek to destroy, thus preserving the joint and allowing time to heal. These formulations typically require a mixture of glycosoaminoglycans and collagen proteins. One formulation in particular includes both hyaluronic acid and at least type I collagen.
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Dingman Brian M.
Mirick O'Connell DeMallie & Lougee LLP
Moore William W.
Nashed Nashaat T.
Schray Kerri P.
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