Polymer derivatives with proximal reactive groups

Details Polymer derivatives with proximal reactive groups Polymer derivatives with proximal reactive groups

2011-08-23

2011-08-23

Nutter, Nathan M (Department: 1765)

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Polymers from only ethylenic monomers or processes of...

Reexamination Certificate

active

08003742

ABSTRACT:
An activated, substantially water-soluble polyoxazoline is provided having a linear or branched poly(ethylene glycol) backbone and at least one terminus linked to the backbone through a hydrolytically stable linkage, wherein the terminus is branched and has proximal reactive groups. The free reactive groups are capable of reacting with active moieties in a biologically active agent such as a protein or peptide thus forming conjugates between the activated polyoxazoline and the biologically active agent.

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