Polymer coated solid matrices and use in immunoassays

Details Polymer coated solid matrices and use in immunoassays Polymer coated solid matrices and use in immunoassays

1987-09-29

1990-05-01

Richman, Barry S.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is organic

422 73, 436524, 436532, G01N 33545

Patent

active

049218093

ABSTRACT:
Certain polyethyleneimines are used to coat solid carriers used in immunoassays to improve the sensitivity of the assay over what is obtained without the coating. Use of the invention in enzyme immunoassays yields sensitivities equal to that of radioimmunoassays. A post-coating is also used after the solid carrier has had a layer of capture molecule applied and before the assay is performed, to improve even further the sensitivity, reliability and dynamic range of the assay results.

REFERENCES:
patent: 3826619 (1984-07-01), Bratu et al.
patent: 3876504 (1974-04-01), Koffler
patent: 4001583 (1974-10-01), Barrett
patent: 4017597 (1974-10-01), Reynolds
patent: 4108975 (1978-08-01), Hales
patent: 4147752 (1978-01-01), Sunvaniemi
patent: 4269605 (1981-05-01), Dean
patent: 4410634 (1981-11-01), Cooper et al.
patent: 4469630 (1983-11-01), Flashner
patent: 4525456 (1982-11-01), Rohrbach
patent: 4526871 (1981-05-01), Avrameas et al.
patent: 4624916 (1984-04-01), Shah et al.
patent: 4629692 (1986-12-01), Dean
patent: 4695392 (1987-09-01), Whitehead
patent: 4719176 (1988-01-01), Klotz
patent: 4753983 (1986-05-01), Ngo

Affiliated with

Also associated with

Rating

Polymer coated solid matrices and use in immunoassays does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Polymer coated solid matrices and use in immunoassays, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polymer coated solid matrices and use in immunoassays will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-829279