Polymer coated particles having immobilized metal ions on the su

Details Polymer coated particles having immobilized metal ions on the su Polymer coated particles having immobilized metal ions on the su

1985-10-11

1987-06-30

Lieberman, Allan M.

Stock material or miscellaneous articles

Coated or structually defined flake, particle, cell, strand,...

Particulate matter

427221, 427302, 428403, 4284111, 4284782, 428522, 428532, B32B 1508, B32B 1902, B32B 1904

Patent

active

046770275

ABSTRACT:
A solid phase can be coated superficially with a polymeric coating by substituting immobilized metal ions on the surface of the solid phase with a hydrophilic polymer or a derivative or aggregate thereof, through a chemisorption process. The solid phase may comprise a magnetic material, such as magnetite, and may have a particle form. The coating can be produced by bringing the solid phase into contact with a solution of a reagent which includes at least one metal chelating and one reactive group, and subsequently bringing the solid phase into contact with a solution of a compound which reacts with the chelater reagent adsorbed on the solid phase. The polymer layer may constitute a polyhydric alcohol, a polyamine, or a polyamide, for example a polysaccharide, such as agarose, a protein or a peptide, a polyacryl amide, etc. and the reactive group may be a vinylsulphone or an epoxide, an aminothiol or a hydroxyl. The metal-chelate forming group is preferably a carboxy-methylated amine and the soluble compound is a water-soluble polymer, such as dextran, polyethylene glycol, dextran or some other polysaccharide.

REFERENCES:
patent: 3783101 (1974-01-01), Tomb et al.

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