Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...
Reexamination Certificate
2002-12-13
2009-02-17
Feely, Michael J (Department: 1796)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Web, sheet or filament bases; compositions of bandages; or...
C424S422000, C424S423000, C424S426000, C424S443000, C528S271000, C528S310000, C528S328000, C528S422000, C528S425000
Reexamination Certificate
active
07491408
ABSTRACT:
A novel A1-B-A2polymer having a number average molecular weight of 10000 to 100000 is provided that has excellent bioabsorbability so as to disappear in a predetermined period of time even when embedded in a large amount in the body, has good kinetic properties, and is useful for preparing tissue anti-adhesion films. This polymer is composed of segments A1and A2each having at least either of modified and unmodified amino acid groups, and segment B composed of PEG having a number average molecular weight of 8000 to 50000. The polymer contains both the modified and unmodified amino acid groups, the content of the modified amino acids is 20 to 85 mol % of all the amino acids in the polymer, and segment A1is bonded to one end of segment B and segment A2is bonded to the other end of segment B.
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Shinji Tanaka et al., “Polyethylene Glycol Middle Segment to suru Triblock Kyojugotai no Gosei to Bussei”, Polymer Preprints, Japan, vol. 51, No. 10, The Society of Polymer Science, Japan 2002, pp. 2515-2516.
Kitano Shigeru
Nakashima Yoshikazu
Ogura Atsuhiko
Tanaka Shinji
Darby & Darby PC
Feely Michael J
NOF Corporation
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