Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Patent
1994-02-09
1997-05-06
Hulina, Amy
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
424466, 424469, 424486, 424499, A61K 914
Patent
active
056268777
ABSTRACT:
Described herein is a drug delivery system useful to deliver drugs at low dosage levels to patients in a sustained fashion and at a controlled rate. The system comprises a wettable polymeric matrix in which is dispersed a multiplicity of particles containing a substantially homogeneous blend of osmotically active excipient and not more than about 10% by weight of drug. The system is particularly well suited for delivery of therapeutic macromolecules such as protein drugs. Delivery of epidermal growth factor is exemplified.
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Amsden Brian G.
Cheng Yu-Ling
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