Polymer affinity system for the delivery of cytotoxic material a

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

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4242801, 424487, 424488, 430 15, 5253295, 5253297, 5263183, 5303911, A61K 3944

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active

056860714

ABSTRACT:
The use of interacting polymers and oligomers to selectively target compounds to desired sites, in-vitro and in-vivo, wherein the first polymer or oligomer is bound to a targeting agent and the second polymer or oligomer is bound to an active agent, such as a drug, a metal or a radioisotope.

REFERENCES:
patent: 4474893 (1984-10-01), Reading
patent: 4687732 (1987-08-01), Ward et al.
patent: 4722899 (1988-02-01), Hamaoka et al.
patent: 5395688 (1995-03-01), Wang et al.
J.L. Klein et al., Human Monoconal Antibodies: Application in Immunotherapy, pp. 271-281, 1994.
D.J. Buchsbaum et al., Antibody, Immunoconjugates and Radiopharmaceuticals, 4:3:245-272, 1991.
S.P. Kramer et al., J. Natl. Cancer Inst., 31:297-326, 1963.
S. Udenfriend et al., Science, 178:871-872, 1972.
T. Kaneko et al., Bioconjugate Chem, 2:133-141, 1991.
R. Julian et al., Analytical Biochemistry, 132:68-73, 1983.
G.L. Ellman, Arch. Biochem. Biophys., 82:70 1959.
E. Tsuchida et al., Makromol. Chem., 175:593-601, 1974 Abstract Only.
R. Subramanian et al., Journal of Polymer Science, Polymer Chemistry Edition, 22:437-451, 1984.
R. Subramanian et al., Journal of Polymer Science, Polymer Chemistry Edition, 17:1855-1860, 1979.
M. Haspel et al., Cancer Res., 45:3951-3961, 1985.
R. Subramanian et al., Bioconjugate Chem., 3:248-255, 1991.
G.A. Hawkins et al., Cancer Research, 53:2368-2373, 1993.
Gottstein et al 1994; Annals of Oncology 5 Suppl 1:597-103.
Davis et al Microbiology 3rd Ed. 1980. Ch. 7 Basis of Chemotherapy.
Seaver 1994 Genetic Engineering News vol. 14 No. 14 pp. 10 & 21.
Sevier et al 1981 Clin Chem vol. 27 No. 11: 1797-1806.
Maeda et al. 1984 J. Protein Chemistry vol. 3 No. 2 181-193.
Subramanian et al 1984 J. Polymer Science vol. 22: 478-479.
Han et al 1990 Makromol Chem Macro Symp. vol. 33:301-309.
Torchilin et al 1993 Proceed Inter Symp Control Rel. of Bioact. Mater vol. 22: 437-451.
Goodwin 1991 Antibody Conjugates and Radiopharmaceuticals vol. 4 No. 4 427-434.

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