Polylactic-polyglycolic acids combined with an acidic phospholip

Details Polylactic-polyglycolic acids combined with an acidic phospholip Polylactic-polyglycolic acids combined with an acidic phospholip

1984-02-15

1986-03-25

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

424 22, 514965, 514953, C07C 3702

Patent

active

045783845

ABSTRACT:
A novel material consisting of a combination of a proteolipid and biodegradable, biocompatible copolymer has been developed for improving and accelerating the healing of osseous tissue. The proteolipid was prepared by combining muco-peptide-N-acetyl-muramoylhydrolase with phosphatidyl inositol, 4,5-diphosphate and the copolymer consists essentially of a 50:50 poly(L)(-)lactide co-glycolide.

REFERENCES:
patent: 3773919 (1973-11-01), Baswell et al.
patent: 3887699 (1975-06-01), Yolles
patent: 3976071 (1976-08-01), Sadek
Hollinger, Jeffrey O., Biomat., Med. Dev., Art. Org., 10(2), pp. 71-83 (1).
Hollinger, Jeffrey O., Journal of Biomedical Materials Research, vol. 17, pp. 71-82 (1983).

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