Polylactic-polyglycolic acids combined with an acidic phospholip

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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424 22, 514965, 514953, C07C 3702

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active

045783845

ABSTRACT:
A novel material consisting of a combination of a proteolipid and biodegradable, biocompatible copolymer has been developed for improving and accelerating the healing of osseous tissue. The proteolipid was prepared by combining muco-peptide-N-acetyl-muramoylhydrolase with phosphatidyl inositol, 4,5-diphosphate and the copolymer consists essentially of a 50:50 poly(L)(-)lactide co-glycolide.

REFERENCES:
patent: 3773919 (1973-11-01), Baswell et al.
patent: 3887699 (1975-06-01), Yolles
patent: 3976071 (1976-08-01), Sadek
Hollinger, Jeffrey O., Biomat., Med. Dev., Art. Org., 10(2), pp. 71-83 (1).
Hollinger, Jeffrey O., Journal of Biomedical Materials Research, vol. 17, pp. 71-82 (1983).

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