Polylactic acid microspheres and process for producing the same

Details Polylactic acid microspheres and process for producing the same Polylactic acid microspheres and process for producing the same

1987-11-10

1991-02-19

Lander, Ferris H.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424426, H61K 916

Patent

active

049942816

ABSTRACT:
Polylactic acid microspheres having an average particle diameter of about 0.1 to 10 .mu.m which are produced from solution containing a physiologically active substance by the solvent-evaporation drying process. The microspheres are produced by emulsifying the solution in a non-solvent by the aid of ultrasonic wave. The microspheres produce a sustained release effect of the physiologically active substance.

REFERENCES:
patent: 4166800 (1979-09-01), Fong
patent: 4384975 (1983-05-01), Fong
patent: 4479911 (1984-10-01), Fong
patent: 4536387 (1985-08-01), Sakamoto et al.

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