Polyketides and antibiotics

Details Polyketides and antibiotics Polyketides and antibiotics

2006-04-04

2006-04-04

Witz, Jean C. (Department: 1651)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C514S029000, C435S075000

Reexamination Certificate

active

07022825

ABSTRACT:
Facile methods for preparing diketide and triketide thioesters are disclosed. The resulting thioesters may be used as intermediates in the synthesis of desired polyketides, and may contain functional groups which ultimately reside in side chains on the resulting polyketide and thus can be used further to manipulate the polyketide so as form derivatives. The polyketides produced may also be tailored by glycosylation, hydroxylation and the like. New polyketides and their derivatives and tailored forms are thereby produced.

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