Polyhydro-2-phenanthrylideneacetic acids and esters thereof

Details Polyhydro-2-phenanthrylideneacetic acids and esters thereof Polyhydro-2-phenanthrylideneacetic acids and esters thereof

1971-01-05

1976-01-13

Gerstl, Robert

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260241, 260468R, 260469, 260471R, 260471C, 260473R, 260473G, 260476C, 260482C, 260488D, 260514S, C07C 6138, C07C 6474

Patent

active

039324826

ABSTRACT:
Alkyl polyhydro-2-phenanthrylideneacetates are prepared by interacting the corresponding 2-oxopolyhydrophenanthrenes with a tri-lower-alkyl .alpha.-phosphono-lower-alkanoate. Said alkyl polyhydro-2-phenanthrylideneacetates are hydrolyzed to the free acid, and then reesterified via the acid chloride with a tertiary-amino-lower-alkanol to give basic esters having cardiotonic activity.

REFERENCES:
patent: 3553251 (1971-01-01), Hauth et al.
patent: 3624128 (1971-11-01), Shaw et al.

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