Chemistry: molecular biology and microbiology – Differentiated tissue or organ other than blood – per se – or...
Reexamination Certificate
2005-09-23
2009-06-23
Saucier, Sandra E. (Department: 1651)
Chemistry: molecular biology and microbiology
Differentiated tissue or organ other than blood, per se, or...
C435S001200
Reexamination Certificate
active
07550255
ABSTRACT:
Polyglycerol, lactose, and a combination of polyglycerol and lactose are effective at preserving cells, tissues, and organs from damage due to hypothermic, ischemic, or other metabolic impairment, and a mixture of polyglycerol plus lactose is particularly useful for the hypothermic storage of cells, tissues, and organs. The mixture of polyglycerol and lactose can be further improved by the addition of chondroitin sulfate, chlorpromazine, calcium, citrate, glutathione, adenine, glucose, magnesium, and a pH buffer.
REFERENCES:
patent: 5145769 (1992-09-01), McNally et al.
patent: 5158867 (1992-10-01), McNally et al.
patent: 5306711 (1994-04-01), Andrews
patent: 6194137 (2001-02-01), Khirabadi et al.
patent: 6616858 (2003-09-01), Fahy et al.
Al-Abdulla, Nael A. B.Sc. et ., The Effects of Supercooling Chemicals on Myocardial Ultrastructure: A Transmission Electron Microscopy Case Study, Connecticut Medicine, 59: 387-399, 1995.
Fahy, Gregory M. et., Cell Biology of Trauma, J.J. Lemasters and C. Oliver (Eds.), CRC Press, 1995, pp. 333-356.
Kaufman, Herbert E. et al., Optisol Corneal Storage Medium, Arch Opthalmol, 109: 864-868, 1991.
Khirabadi, Bijan S. and Fahy, Gregory M., Cryopreservatio nof the Mammalian Kidney. 1. Transplantation of Rabbit Kidneys Perfused with EC and RPS-2 at 2-4° C1, Cryobiology, 31: 10-25, 1994.
Klebe and Mancuso, “Identification of new cryoprotective agents for cultured mammalian cells.” In Vitro, 19: 167-170, 1983.
Toledo-Pereyra, Luis H. and Ramakrishnan, Vellore R., Effect of Chondroitin Sulfate on the Prolongation of Kidney Allograft Survival, Transplantation, 27 (6): 427-429. 1979.
Klebe and Mancuso, “Identification of new cryoprotective agents for cultured mammalian cells.” In Vitro, 19:167-170, 1983.
International Search Report for international application PCT/US03/02939.
Pegg, D.E., Jacobsen, I.A., Halasz, N.A., Organ Preservation - Basic and Applied Aspects, MTP Press, Lancaster, 1982, pp. 323-324.
21st Century Medicine, Inc.
Foley & Lardner LLP
Reiter Stephen E.
Saucier Sandra E.
LandOfFree
Polyglycerol compositions for the protection of living... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Polyglycerol compositions for the protection of living..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Polyglycerol compositions for the protection of living... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4110770