Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.
Patent
1995-06-01
1996-09-24
Housel, James C.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Lymphokines, e.g., interferons, interlukins, etc.
530350, 530403, 530405, 530409, 424 851, 424 852, 424 854, 424 857, 435188, C07K 100, A61K 4505, A61K 3821, C12N 996
Patent
active
055592139
ABSTRACT:
The present invention is a physiologically active, substantially non-immunogenic water soluble polyethylene glycol protein conjugate having the same utility as the protein which forms the conjugate, without having the same properties of producing an immunogenic response possessed by the protein which forms this conjugate.
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Hakimi John
Kilian Patricia
Rosen Perry
Epstein William H.
Hoffmann-La Roche Inc.
Housel James C.
Johnston George W.
Shaver Jennifer
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