Polyethylene glycol ointment for apthous ulcers

Details Polyethylene glycol ointment for apthous ulcers Polyethylene glycol ointment for apthous ulcers

1990-09-20

1992-05-12

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

424484, 424486, 514928, 514941, 514969, 514626, A61K 906, A61K 4732, A61K 4734, A61K 31575

Patent

active

051126206

ABSTRACT:
A therapeutic ointment having wet adherent properties and particularly well suited for delivery of medicaments to mucosal surfaces includes a base material comprising from about 3 to 15% by weight of a water soluble salt of a copolymer of methyl vinyl ether and maleic acid or anhydride in a polyethylene glycol ointment. Formulations of the base material with triamcinolone acetonide and lidocaine are particularly efficacious in the treatment of recurrent aphthous ulcers.

REFERENCES:
patent: Re33093 (1989-10-01), Schiraldi et al.
patent: 4307075 (1981-12-01), Martin
patent: 4627977 (1986-12-01), Gaffar et al.
patent: 4764378 (1988-08-01), Keith et al.
patent: 4765983 (1988-08-01), Takayanagi et al.
patent: 4883660 (1989-11-01), Blackman et al.
patent: 4910247 (1990-03-01), Haldar et al.
patent: 4948580 (1990-08-01), Browning
"Topical Mucosal Adhesive Dosage Forms", T. Nagi, Medicinal Research Reviews, vol. 6, No. 2, 227-242 (1986).

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