Polyethylene glycol-hirudin conjugates, process for preparing th

Details Polyethylene glycol-hirudin conjugates, process for preparing th Polyethylene glycol-hirudin conjugates, process for preparing th

1993-02-17

1994-11-08

Wityshyn, Michael G.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Chemical modification or the reaction product thereof, e.g.,...

530345, C07K 1300, A61K 3764, A61K 4748

Patent

active

053628586

ABSTRACT:
The present invention relates to a process for preparing a polyethylene glycol (or derivatives)-hirudin conjugate. It also relates to the polyethylene glycol (or derivatives)-hirudin conjugate obtained and its use as medicinal product for the treatment of thromboses.

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patent: 5169627 (1992-12-01), Cunningham
Freiser, Hajestam et al., Bio Chromatography, vol. 2(4), pp. 186-189, (1987).

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