Organic compounds -- part of the class 532-570 series – Organic compounds – Four or more ring nitrogens in the bicyclo ring system
Patent
1993-09-13
1994-08-30
Shah, Mukund
Organic compounds -- part of the class 532-570 series
Organic compounds
Four or more ring nitrogens in the bicyclo ring system
435134, C07D25126
Patent
active
053429400
ABSTRACT:
High purity polyethylene glycol derivatives of formula (I) are useful as protein modifiers of interferons, t-PA, EGF, various hormones, etc. The thus modified protein has minimized antigenicity, prolonged plasma half life, or improved transfer to tissue. A novel process for preparing high purity polyethylene glycol derivatives is also disclosed.
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Kai Yoshiyuki
Maeda Hiroo
Ono Keiichi
Gupta Y. N.
Seikagaku Corporation
Shah Mukund
Sumitomo Pharmaceuticals Company Limited
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