Polyethylene glycol carbamates

Details Polyethylene glycol carbamates Polyethylene glycol carbamates

1988-07-20

1993-02-09

Shippen, Michael L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

N-c doai

514507, 514517, 556 45, 556138, 556 1, 558 50, 558262, 560 13, 560 16, 560 29, 560148, 560159, 560169, A61K 3100

Patent

active

051853680

ABSTRACT:
Compounds of the formula ##STR1## in which R is alkyl having up to 4 carbon atoms, n has an average value of at least 9, X is a radical of the formula --C(.dbd.O)--(NH--SO.sub.2).sub.m -- in which m is 0 or 1 and, if m is 1, the carbonyl group may be bonded to the oxygen atom or to the nitrogen atom, and each of the radicals A.sub.1, A.sub.2 and A.sub.3, independently of the others, is hydrogen or an acyl radical, and salts of salt-forming compounds of formula I, as well as metal complexes of compounds of formula I, in which A.sub.1, A.sub.2 and A.sub.3, are hydrogen can be used as metal chelators and as auxiliaries in diagnosis.

REFERENCES:
patent: 3634407 (1972-01-01), Gaemnann
patent: 4419365 (1983-12-01), McLachlan
patent: 4612122 (1986-09-01), Ambrus et al.
patent: 4671901 (1987-06-01), Green
patent: 4684482 (1987-08-01), Green
patent: 4764523 (1988-08-01), Heinrich
patent: 4954634 (1990-09-01), Heinrich et al.
Helv. Chim. Acta. vol. 46 pp. 1385-1389 (1963).
Merck Index 10th ed p. 412 Item #2839 (1983).

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