Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Reexamination Certificate
2002-04-29
2004-08-31
Salimi, Ali R. (Department: 1648)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
C424S186100, C530S300000, C536S023720
Reexamination Certificate
active
06783763
ABSTRACT:
BACKGROUND OF THE INVENTION
The present invention has for its object polyepitopic protein fragments, such as those of the E6 and E7 proteins of human papillomavirus, or of the human p53 protein, their process of production, and their uses, particularly in the field of therapeutic or preventive vaccination.
SUMMARY OF THE INVENTION
The invention more particularly has for its object the use of polyepitopic fragments of a predetermined protein for the preparation of medications adapted for the prevention or treatment of pathologies in which said protein is recognized by the cellular immune system.
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by Beatrice Culmann et al., “Indentification of multirestricted immunodominant regions recognized by cytolytic T lymphocytes in the Human Immunodeficiency Virus type 1 Nef protein”,Journal of Virology, vol. 68, No. 11, Nov. 1994, pp. 736-7343.
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by M. Muller et al., “Identification of seroreactive regions of the human papillomavirus type 16 proteins E4, E6, E7 and L1”,Journal of General Virology, Society for General Microbiology, Reading, vol. 71, Jan. 1990, pp. 2709-2717.
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Bourgault Villada Isabelle
Choppin Jeannine
Connan Francine
Ferries Estelle
Guillet Jean-Gerard
Peptide Immune Ligands
Salimi Ali R.
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