Polyene oxazoles and processes for their preparation

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S374000

Reexamination Certificate

active

10865767

ABSTRACT:
Polyene oxazoles of the following formulawherein R3is selected from H and methyl, are disclosed. Such compounds, and pharmaceutically acceptable salts thereof, may be used in the inhibition of tumor cell growth. The polyene oxazoles and their pharmaceutically acceptable salts may be formulated as pharmaceutical compositions with pharmaceutically acceptable carriers for use in the inhibition of tumor cells. The polyene oxazoles may be obtained from strains ofStreptomyces sparsogenes, such as strain 022 having deposit number IDAC 270504-04.

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