Polydiacetylene-containing solid colorimetric and /or...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism

Reexamination Certificate

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Details

C435S288700

Reexamination Certificate

active

08008039

ABSTRACT:
A colorimetric and/or fluorescent detector, which comprises a film of polydiacetylenes and lipids deposited on a substrate, wherein said film is coated with one or more layers, wherein at least one of said layers is capable of supporting the growth of microorganisms. Also provided are processes for preparing the novel colorimetric and/or fluorescent detector and uses thereof in the detection of bacteria.

REFERENCES:
patent: 6022748 (2000-02-01), Charych et al.
patent: 6361962 (2002-03-01), Lentini et al.
patent: WO 97/27316 (1997-07-01), None
patent: WO 98/39632 (1998-09-01), None
patent: WO 00/55623 (2000-09-01), None
patent: WO 2005/005982 (2005-01-01), None
Jelinek R et al.: “Interfacial Catalysis by Phospholipases at Conjugated Lipid Vesicles: Colorimetric Detection and NMR Spectroscop”, Chemistry and Biology, Current Biology, London, GB, vol. 5, Nov. 1998, pp. 619-629.
Jelinek R et al.: “Polymerized Lipid Vesicles as Colorimetric Biosensors for Biotechnological Applications”, Biotechnology Advances, Elsevier Publishing, Barking, GB, vol. 19 (2), 1 Apr. 2001, pp. 109-118.
Rozner S et al.: “Detection and Analysis of Membrane Interactions by a Biometic Colorimetric Lipid/Polydiacetylene Assay”, Analytical Biotechnology, Academic Press, San Diego, CA, US, vol. 319 (1), Aug. 1, 2003, pp. 96-104.
Pan J. J. et Charych D.: “Molecular recognition and Colorimetric Detection of Cholera Toxin by Poly(acetylene) liposomes incorporating Gm1 ganglioside”, Langmuir, vol. 13, 1997, pp. 1365-1367.

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