Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2005-03-15
2005-03-15
Wilson, Michael C. (Department: 1632)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C435S320100
Reexamination Certificate
active
06867288
ABSTRACT:
The present invention provides methods and compositions for treating cyst formation in PKD1-associated epithelial cells. Such methods encompass administering an isolated human PKD1 gene, or fragments of the gene, under conditions that result in expression of therapeutically effective amounts of all, or part of, the PKD1 protein. The invention also encompasses compositions for treating cyst formation associated with APKD.
REFERENCES:
patent: 6071717 (2000-06-01), Klinger et al.
Cecil: Textbook of Medicine, J.B. Wyngaarden et al., ed., W.B. Saunders Co., Philadelphia 1988, pp. xxxv, 1039.*
The European Polycystic Kidney Diseae Consortium, 1994, Cell:881-894, Jun. 1994.*
Orkin et al., 1995, “Report and Recommendation of the Panel to Assess the NIH Investment in Research on Gene Therapy”, National Institutes of Health, Dec. 1995.
Burn Timothy C.
Connors Timothy D.
Dackowski William
Germino Gregory
Klinger Katherine W.
Genzyme Corporation
Johns Hopkins University
Wilson Michael C.
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